The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2001
Filed:
Dec. 16, 1997
Applicant:
Inventors:
Michael D. Parker, Frederick, MD (US);
Jonathan F. Smith, Sabillasville, MD (US);
Bruce J. Crise, Frederick, MD (US);
Mark Steven Oberste, Lilburn, GA (US);
Shannon M. Schmura, Hagerstown, MD (US);
Assignee:
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ; C12N 7/04 ; C12N 1/540 ;
U.S. Cl.
CPC ...
A61K 3/912 ; C12N 7/04 ; C12N 1/540 ;
Abstract
cDNAs coding for an infectious Western Equine Encephalitis virus (WEE) and infectious Venezuelan Equine Encephalitis virus variant IE (VEE IE) are disclosed in addition to cDNA coding for the structural proteins of Venezuelan Equine Encephalitis virus variant IIIA (VEE IIIA). Novel attenuating mutations of WEE and VEE IE and their uses are described. Also disclosed are attenuated chimearic alphaviruses and their uses.