The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2001

Filed:

Aug. 18, 1992
Applicant:
Inventors:

Bruce E. Furie, Wellesley, MA (US);

Barbara C. Furie, Wellesley, MA (US);

Howard A. Liebman, Newton, MA (US);

Richard M. Lewis, Leesburg, VA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/514 ;
U.S. Cl.
CPC ...
A61K 3/514 ;
Abstract

A method of isolating a protein from a mixture containing the protein, the method including providing an antibody immobilized on a solid support, which antibody is reactive with the protein complexed with a ligand and substantially unreactive with the protein not complexed with the ligand; contacting the mixture, in the presence of the ligand, with the immobilized antibody to bind the protein, complexed with the ligand, to the immobilized antibody to form an immune complex; and contacting the immune complex with a compound having a binding affinity for the ligand higher than the binding affinity of the protein for the ligand, to release the protein from the immobilized antibody.


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