The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2001
Filed:
Dec. 01, 1998
Applicant:
Inventors:
Jonathan Oliner, Mountain View, CA (US);
Fred Christians, Los Altos, CA (US);
Vivi Truong, San Jose, CA (US);
Daniel Haber, Chestnut Hill, MA (US);
James Bean, Arlington, MA (US);
David Miklos, W. Roxbury, MA (US);
Denis Paul Harkin, Belfast BT5 6HX, Northern Ireland, GB;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; G01N 3/353 ; C12P 2/106 ; A61K 4/900 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; G01N 3/353 ; C12P 2/106 ; A61K 4/900 ; C07H 2/104 ;
Abstract
Analysis of the genes whose expression is affected by BRCA1 has identified a set of genes, each of which is up- or down-regulated by BRCA1. Each of these genes, alone or in groups, can be used to determine the mutational status of a BRCA1 gene, to determine whether a particular allelic variant affects BRCA1 function, to diagnose neoplasia, and to help identify candidate drugs which may be useful as anti-neoplastic agents.