The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2001
Filed:
Aug. 29, 1997
Applicant:
Inventors:
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12N 1/500 ; C12N 1/563 ; C12N 5/00 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12N 1/500 ; C12N 1/563 ; C12N 5/00 ;
Abstract
An isolated DNA molecule that directs neuron-specific transcription of a downstream heterologous DNA segment (a promoter segment) in a mammalian cell is disclosed. The isolated DNA molecule contains a promoter segment from the mouse genomic Presenilin-1 DNA, or a DNA sequence that hybridize to such DNA and directs neuron-specific transcription of a downstream heterologous DNA segment in a mammalian cell. DNA constructs comprising such promoter segments and various uses thereof are also disclosed.