The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2001
Filed:
Apr. 21, 2000
Applicant:
Inventors:
Gregory S. Hamilton, Catonsville, MD (US);
Joseph P. Steiner, Hampstead, MD (US);
Eric S. Burak, Forest Hill, MD (US);
Assignee:
GPI NIL Holdings, Inc., Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/155 ; A61K 3/147 ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/155 ; A61K 3/147 ; C07D / ; C07D / ; C07D / ;
Abstract
This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.