The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2001
Filed:
Aug. 28, 2000
Péter Mátyus, Budapest, HU;
László Hársing, Budapest, HU;
Marianne Tapfer née Karim, Budapest, HU;
Judit Kosáry, Budapest, HU;
Ágnes Papp née Behr, Budapest, HU;
Antal Simay, Budapest, HU;
Yemane Tilahun, Budapest, HU;
Éva Tomori née Joszt, Budapest, HU;
Edit Horváth, Budapest, HU;
Katalin Horváth, Budapest, HU;
Ildikó Varga, Budapest, HU;
Erzsébet Zára née Kaczián, Budapest, HU;
Margit Bidló née Iglóy, Budapest, HU;
Alice Druga, Budapest, HU;
György Rabloczky, Budapest, HU;
Márta Varga, Budapest, HU;
Egon Kárpáti, Budapest, HU;
Endre Kasztreiner, Budapest, HU;
István Király, Budapest, HU;
Ildikó Máthé née Gyóry, Budapest, HU;
György Máthé, Budapest, HU;
László Sebestyén, Budapest, HU;
Nándor Makk, Kismaros, HU;
Gyogyszerkutato Intezet Kft., Budapest, HU;
Abstract
The invention relates to R-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (1), and to S-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (2), and to acid-addition salts thereof as well as pharmaceutical compositions containing these compounds. Furthermore, the invention relates to a process for the preparation of the above compounds. The new starting compounds of formulae (4) and (5) are also involved in the scope of the invention. The compounds according to the invention possess &agr;,- and &agr;,-adrenoceptor antagonistic effects and urogenital selectivity. Thus, they are useful for the treatment of the benign prostate hyperplasia.