The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2001
Filed:
Dec. 23, 1998
Applicant:
Inventors:
Francis Michon, Bethesda, MD (US);
Milan Blake, Fulton, MD (US);
Assignee:
Baxter International, Inc., Deerfield, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/904 ; C08B 3/700 ;
U.S. Cl.
CPC ...
C12P 1/904 ; C08B 3/700 ;
Abstract
A procedure to isolate large quantities of capsular poly saccharides (CPS) from culture supernatants as well as bacterial cells of gram-negative and gram-positive bacteria using base extraction is described. The procedure is simple, rapid, reproducible and applicable to a variety of bacterial species. The method also yields novel CPS characterized by their lack of covalent attachment to extraneous peptidoglycan. Vaccines and methods of immunization against bacterial infection using the CPS obtained by the process of the invention are also disclosed.