The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2001
Filed:
Dec. 28, 1992
Applicant:
Inventors:
Marco Adami, Milan, IT;
Roberto Magrini, Milan, IT;
Paolo Maranghi, Milan, IT;
Antonino Suarato, Milan, IT;
Assignee:
Pharmacia & Upjohn S.p.A., Milan, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/08 ; A61K 9/10 ; A61P 3/500 ;
U.S. Cl.
CPC ...
A61K 9/08 ; A61K 9/10 ; A61P 3/500 ;
Abstract
A lyophilized composition comprising (a) a conjugate comprising a N-alkyl methacrylamide-based copolymer and an anthracycline glycoside linked through a peptide spacer to the copolymer and (b) a cosolubilizing agent may optionally also contain (c) a filler. Also optionally, a targeting moiety may be linked to the copolymer of the conjugate via a peptide spacer. An injectable solution of the conjugate is obtained by reconstitution of the lyophilized composition.