The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2001
Filed:
Dec. 14, 1999
Applicant:
Inventors:
Gordon Nelson Arbuthnot, Indianapolis, IN (US);
Karen Klapper Lomas, Wilmington, NC (US);
Glenn Alan Meyer, Wilmington, NC (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/20 ; A61K 9/14 ; A61K 9/16 ;
U.S. Cl.
CPC ...
A61K 9/20 ; A61K 9/14 ; A61K 9/16 ;
Abstract
The present invention relates to a pharmaceutical formulation, which comprises from 5 to 15% by weight of tamoxifen citrate and a first disintegrant which is croscarmellose sodium, the percentage by weight of croscarmellose sodium present in the formulation being chosen such that, in six 20 mg unit doses, an average of at least 65 percent by weight of the tamoxifen citrate in the formulation will dissolve within 10 minutes in 1000 mL of 0.02N hydrochloric acid at 37° C. when stirred at 100 rpm.