The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2001
Filed:
Feb. 21, 1997
Applicant:
Inventors:
Joan Massague, New York, NY (US);
James M. Roberts, Seattle, WA (US);
Andrew Koff, New York, NY (US);
Kornelia Polyak, Baltimore, MD (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/618 ; C07K 1/640 ; G01N 3/353 ; G01N 3/3577 ;
U.S. Cl.
CPC ...
C07K 1/618 ; C07K 1/640 ; G01N 3/353 ; G01N 3/3577 ;
Abstract
The subject invention provides an isolated protein having an apparent molecular weight of about 27 kD and capable of binding to and inhibiting the activation of a cyclin E-Cdk2 complex. The subject invention further provides an isolated antibody and a purified preparation of polyclonal and monoclonal antibodies which are specifically immunoreactive with a p27 protein. The subject invention further provides a kit for detecting a p27 protein.