The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2001
Filed:
Apr. 30, 1999
Applicant:
Inventors:
Richard A. Craig, Racine, WI (US);
Jack Henkin, Highland Park, IL (US);
Megumi Kawai, Libertyville, IL (US);
Linda M. Lynch, Pleasant Prairie, WI (US);
Jyoti Patel, Libertyville, IL (US);
George S. Sheppard, Willmette, IL (US);
Jieyi Wang, Gurnee, IL (US);
Assignee:
Abbott Laboratories, Abbott Park, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1165 ; C07C / ;
U.S. Cl.
CPC ...
A61K 3/1165 ; C07C / ;
Abstract
A class of substituted b-amino acids are potent inhibitor of methionine aminopeptidase type 2 (MetAP2) and are thus useful in inhibiting angiogenesis and disease conditions which depend upon angiogenesis for their development such as diabetic retinopathy, tumor growth, and conditions of inflammation. Pharmaceutical compounds containing the compounds and methods of inhibiting methionine aminopeptidase-2, and angiogenesis are also disclosed.