The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2001
Filed:
Jun. 22, 1999
Applicant:
Inventors:
John W. Shultz, Verona, WI (US);
Fen Huang, Madison, WI (US);
Assignee:
Promega Corp., Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 ; C12N 9/96 ;
U.S. Cl.
CPC ...
C12N 9/12 ; C12N 9/96 ;
Abstract
The present invention provides methods and compositions for protein stabilization, particularly the stabilization of polymerases in aqueous solutions with cationic surfactants. The present invention further provides cationic surfactants, including polyethoxylated amines, that stabilize thermostable and thermolabile enzymes in solution. These surfactants stabilize the activity of various enzymes, including thermostable DNA polymerases, thermolabile DNA polymerases and reverse transcriptases.