The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2001
Filed:
Feb. 23, 2000
Applicant:
Inventors:
Lowell J. Lawrence, Lexington, KY (US);
Stefan Kwiatkowski, Lexington, KY (US);
Steven G. Mobley, Lexington, KY (US);
Assignee:
PTRL East, Inc., Richmond, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
C07D / ;
Abstract
Dikegulac, its salts and related derivatives are prepared by reacting 2-Keto-L-gulonic acid with 2,2 dimethoxypropane at an elevated temperature in the presence of a catalytic amount of a strong acid. This produces a reaction intermediate which is then reacted with a base to complete hydrolysis and produce an acid salt of dikegulac. Simple concentration and phase separation techniques are used to provide a more efficient, environmentally friendly and cost effective process.