The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2001
Filed:
Dec. 28, 1998
Applicant:
Inventors:
Paul J. Davis, Bedford, GB;
Cornelis P. Logt van der, Northampton, GB;
Martine E. Verhoeyen, Northampton, GB;
Assignee:
Unilever Patent Holdings B.V., Vlaardingen, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/600 ; C07K 1/00 ; C12P 2/108 ; A61K 3/9395 ; G01N 3/353 ;
U.S. Cl.
CPC ...
C07K 1/600 ; C07K 1/00 ; C12P 2/108 ; A61K 3/9395 ; G01N 3/353 ;
Abstract
A multivalent antigen-binding protein comprises a first polypeptide comprising, in series, three or more variable domains of an antibody heavy chain and a second polypeptide comprising, in series, three of more variable domains of an antibody light chain, said first and second polypeptides being linked by association of the respective heavy chain and light chain variable domains, each associated variable domain pair forming an antigen binding site. Methods for their production and uses thereof, in particular for therapeutic and diagnostic applications, are disclosed.