The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2001

Filed:

Nov. 19, 1998
Applicant:
Inventors:

Klaus Hellerbrand, Geltendorf, DE;

Appollon Papadimitriou, Bichl, DE;

Gerhard Winter, Dossenheim, DE;

Assignee:

Boehringer Mannheim GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/34 ; C12N 9/96 ; C12N 5/02 ; G01N 3/353 ; A61K 3/9395 ;
U.S. Cl.
CPC ...
C12Q 1/34 ; C12N 9/96 ; C12N 5/02 ; G01N 3/353 ; A61K 3/9395 ;
Abstract

An aqueous protein solution buffered with a potassium phosphate buffer, in which the ratio of potassium ions to sodium ions in the solution is at least 10:1, is resistant to the formation of protein aggregates and particles under conditions of freezing, thawing, lyophilization, and reconstitution.


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