The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2001
Filed:
Nov. 29, 1997
Applicant:
Inventors:
Mahendra S. Rao, Salt Lake City, UT (US);
Mark Noble, Sandy, UT (US);
Margot Mayer-Proschel, Sandy, UT (US);
Assignee:
University of Utah Research Foundation, Salt Lake City, UT (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/06 ; C12N 5/08 ;
U.S. Cl.
CPC ...
C12N 5/06 ; C12N 5/08 ;
Abstract
A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5,E-NCAM,glial-restricted precursor (GRP) cells are capable of differentiating into oligodendrocytes, A2B5,process-bearing astrocytes, and A2B5,fibroblast-like astrocytes, but not into neurons. GRP cells can be maintained by regeneration in culture. GRP cells differ from oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells in growth factor requirements, morphology, and progeny. Methods of use of GRP cells are also disclosed.