The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2001
Filed:
Apr. 03, 1998
Applicant:
Inventors:
Jinkang Wang, San Francisco, CA (US);
Yi-Lin Zhang, San Mateo, CA (US);
Assignee:
Valentis, Inc., Burlingame, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 ; A61K 9/133 ;
U.S. Cl.
CPC ...
A61K 9/127 ; A61K 9/133 ;
Abstract
Methods and compositions are provided for the introduction of polyanionic molecules, in particular, nucleic acids, into mammalian cells using certain phosphatidyl ethanolamines as helper lipids in conjunction with various cationic lipids. In particular, cationic lipid-mediated transfection of mammalian cells is improved by the use of lipid carriers comprising DLPE or DiPPE and cationic lipids.