The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2001
Filed:
Oct. 01, 1997
Lois K. Miller, Athens, GA (US);
Albert Lu, Newark, DE (US);
Bruce Christian Black, Yardley, PA (US);
Peter Michael Dierks, Yardley, PA (US);
Other;
Abstract
Provided herein are genetically engineered baculoviruses which express insect-specific toxins, preferably paralytic neurotoxins, under the regulatory control of strong promoters expressed early after infection and in a wide variety of insect cells. Particularly preferred insect-specific paralytic neurotoxins are those of insect-predacious mites, including Pyemotes. The genetically engineered baculoviruses of the present invention are improved over prior art viruses in that they produce efficacious insect-toxic levels of the neurotoxin at earlier times after infection, particularly in comparison to baculoviruses in which the toxin is expressed under the control of a polyhedrin or granulin promoter. Insect-toxic compositions are also provided and methods of insect control using these compositions are described.