The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2001
Filed:
Oct. 06, 1997
Maurice Cohen, Highland Park, IL (US);
Tracey L. Colpitts, Round Lake, IL (US);
Paula N. Friedman, Deerfield, IL (US);
Edward Granados, Vernon Hills, IL (US);
Michael R. Klass, Libertyville, IL (US);
John C. Russell, Pleasant Prairie, WI (US);
Kent D. Stewart, Gurnee, IL (US);
Stephen D. Stroupe, Libertyville, IL (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as PS133 and transcribed from prostate tissue is described. One polypeptide of the present invention is a member of the human serine protease family. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS133-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS133 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumors or metastases.