The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2001
Filed:
Oct. 01, 1996
Julian R. Sampson, Cardiff, CF5 2EL, GB;
Mark David Nellist, 3053 RG Rotterdam, NL;
Phillip Brook-Carter, Wonthaggi, VIC 3995, AU;
Magitha Maheshwar, Mid Glamorgan, CF7 9UB, GB;
Dirkje Jorijntje Johanna Halley, 3039 KD Rotterdam, NL;
Lambertus Antonius Jacobus Janssen, 2991 DJ Barendrecht, NL;
Arjenne Lique Wilhelma Hesseling, 3207 Spijkenisse, NL;
Anna Maria Wilhelmina van den Ouweland, 3212 LC, Simonshaven, NL;
Peter Charles Harris, Oxforrd OX4 4BS, GB;
Christopher James Ward, Oxford, OX3 7EH, GB;
Martin Hendrik Breuning, 1503 BR, Zaandam, NL;
Jeroen Hendrik Roelfsema, 2321 RR, Leiden, NL;
Other;
Abstract
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterised by widespread development of growths in many tissues and organs. A gene (TSC2) is identified on chromosome 16 which is mutated in TSC and which may behave as a tumour suppressor. Screening of actual or suspected TSC patients for normal or mutated TSC2 can be used for diagnostic purposes. TSC2 protein (tuberin) may be used to treat or prevent unrestrained cell division and/or tumour development in patients with or without TSC.