The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2001

Filed:

Sep. 03, 1996
Applicant:
Inventor:

Dale E. Bredesen, Rancho Santa Fe, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/844 ; A61K 3/9395 ; A61K 3/9385 ; A01N 3/718 ;
U.S. Cl.
CPC ...
A61K 3/844 ; A61K 3/9395 ; A61K 3/9385 ; A01N 3/718 ;
Abstract

Methods for controlling cell death when the cell is exposed to one or more potentially lethal cellular insults. In one method, cell death is inhibited by introducing a reactive oxygen species limiter into the cell which prevents the build up of lethal levels of reactive oxygen species when the cell is exposed to a cellular insult. In another method, cell death is promoted in cancer cells or other proliferating cells which are naturally resistant to lethal cellular insults. The method involves neutralizing reactive oxygen species limiters, such as bcl-2, which occur naturally in cancer cells and which prevent the build up of reactive oxygen species within the cancer cells when they are exposed to lethal cellular insult. Neutralizing the reactive oxygen species limiter leaves the cancer cell unable to protect itself when cellular insult causes increases in the level of reactive oxygen species. The result is an increase in cell death.


Find Patent Forward Citations

Bredesen, Dale. (2001). Method for reducing bcl-2 expressing cells resistance to death (U.S. Patent No. 6231852). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6231852

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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