The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2001

Filed:

Feb. 07, 1997
Applicant:
Inventors:

Shuji Hinuma, Tsukuba, JP;

Yugo Habata, Tsukuba, JP;

Yuji Kawamata, Tsukuba, JP;

Masaki Hosoya, Tsuchiura, JP;

Ryo Fujii, Tsukuba, JP;

Shoji Fukusumi, Tsukuba, JP;

Chieko Kitada, Sakai, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/447 ; C12N 1/512 ; A61K 3/817 ;
U.S. Cl.
CPC ...
C07K 1/447 ; C12N 1/512 ; A61K 3/817 ;
Abstract

The present invention relates to the ligand polypeptide for the human pituitary- and mouse pancreas-derived G protein-coupled receptor proteins. The ligand polypeptide or the DNA which codes for the ligand polypeptide can be used for (1) development of medicines such as pituitary function modulators, central nervous system function modulators, and pancreatic function modulators, and (2) development of recombinant receptor proteins and screening of pharmaceutical candidate compounds. In particular, by the receptor binding assay systems utilizing the expression of recombinant G protein-coupled receptor proteins in accordance with the invention, agonists and antagonists of G protein-coupled receptors which are specific to human and other warm-blooded animals can be screened and the agonists or antagonists obtained can be used as therapeutic and prophylactic agents for various diseases.


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