The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2001
Filed:
Dec. 30, 1999
Applicant:
Inventors:
Akihiko Tsuji, Shizuoka, JP;
Masahiko Hirano, Shizuoka, JP;
Hiroyuki Koshimoto, Kanagawa, JP;
Kaname Ishibashi, Shizuoka, JP;
Assignee:
Laboratory of Molecular Biophotonics, Shizuoka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C07H 2/102 ; C07H 2/104 ; C12N 1/500 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C07H 2/102 ; C07H 2/104 ; C12N 1/500 ;
Abstract
Detection probes labeled with fluorescent dyes, to which are bound nuclear membrane unpermeable molecules via linkers, having base sequences that can hybridize to a target nucleic acid. The probes are introduced into the cytoplasm of a living cell in which the target nucleic acid is present, and the target nucleic acid is detected by measurement of the change in fluorescence of the fluorescent dyes due to the formation of a hybrid of the target nucleic acid and the probes.