The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2001
Filed:
Dec. 15, 1998
Applicant:
Inventors:
Dick de Vos, Oegstgeest, NL;
Stephen Brown, Lowton, GB;
Allan M. Jordan, Calcot, GB;
Nicholas J. Lawrence, Prestwich, GB;
Alan Th. McGown, Didsbury, GB;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07B 5/700 ; C07C / ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07B 5/700 ; C07C / ;
Abstract
The object of the present invention is the development of new chiral auxiliaries for improved &bgr;-lactam formation that control both the diastereoselectivity of &bgr;-lactam formation and which can be removed without destruction of the sensitive azetidinone ring, providing valuable intermediates for coupling to the C-13 hydroxyl group of anti-tumor taxanes, such as paclitaxel. Further, the object of the present invention is enantiomerically pure (S)-(−)-1-(p-methoxy-phenyl)propyl-1-amine.