The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2001
Filed:
Feb. 10, 1999
Norbert W. Bischofberger, San Carlos, CA (US);
Robert J. Jones, Millbrae, CA (US);
Murty N. Arimilli, Fremont, CA (US);
Kuei-Ying Lin, Fremont, CA (US);
Michael S. Louie, San Mateo, CA (US);
Lawrence R. McGee, Pacifica, CA (US);
Ernest J. Prisbe, Los Altos, CA (US);
William A. Lee, Los Altos, CA (US);
Kenneth C. Cundy, Belmont, CA (US);
Gilead Sciences, Inc., Foster City, CA (US);
Abstract
Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.