The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2001
Filed:
Oct. 04, 1991
Applicant:
Inventor:
Irving Boime, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/104 ; A61K 3/800 ; C07K 1/600 ; C08G 6/348 ;
U.S. Cl.
CPC ...
C12P 2/104 ; A61K 3/800 ; C07K 1/600 ; C08G 6/348 ;
Abstract
The invention provides peptide and protein pharmaceuticals with extended half-lives. The modified peptides and proteins of the invention contain at least two tandem extensions at their C-terminus comprising the carboxy terminal portion of human chorionic gonadotropin. These “CTP units” consist essentially of the native HCG-&bgr; sequence from position 112-118 to position 145 or conservative modifications thereof.