The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2001

Filed:

Feb. 28, 2000
Applicant:
Inventors:

Jeffrey Alan Oplinger, Cary, NC (US);

Barry George Shearer, Cary, NC (US);

Eric Cleveland Bigham, Chapel Hill, NC (US);

Eric Steven Furfine, Durham, NC (US);

Edward Patrick Garvey, Chapel Hill, NC (US);

Assignee:

Glaxo Wellcome Inc., Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/144 ; A61K 3/1395 ; A61K 3/1215 ;
U.S. Cl.
CPC ...
A61K 3/144 ; A61K 3/1395 ; A61K 3/1215 ;
Abstract

The use of an N-substituted urea derivative for the manufacture of a medicament for the treatment of a condition where there is an advantage in inhibiting the NO synthase enzyme, in particular cerebral ischemia, and pharmaceutical formulations therefor are disclosed. Novel N-substituted urea derivatives and processes for the preparation thereof are also described.


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