The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2001
Filed:
Jan. 08, 1999
Applicant:
Inventors:
Ryohei Kato, Toda, JP;
Tsutomu Mimoto, Toda, JP;
Tominaga Fukazawa, Toda, JP;
Naoko Morohashi, Toda, JP;
Yoshiaki Kiso, Toda, JP;
Assignee:
Japan Energy Corporation, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1425 ; A61K 3/140 ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1425 ; A61K 3/140 ;
Abstract
The present invention provides synthetic methodology to produce novel dipeptide compounds and pharmaceutically acceptable salts thereof which exhibit excellent HIV protease inhibitory activity and excellent bioavailability from digestive tracts. Methods of using the dipeptide compounds and pharmaceutically acceptable salts thereof also are provided. A non-limiting example of a dipeptide compound of the invention has the general formula (IA):