The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2001
Filed:
Sep. 22, 1997
Applicant:
Inventors:
Leu-Fen H. Lin, Cambridge, MA (US);
Franklin D. Collins, Bellvue, WA (US);
Daniel H. Doherty, Boulder, CO (US);
Jack Lile, Boulder, CO (US);
Susan Bektesh, Boulder, CO (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/00 ; A61K 9/00 ; C12N 1/104 ;
U.S. Cl.
CPC ...
A61F 2/00 ; A61K 9/00 ; C12N 1/104 ;
Abstract
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified. Genes encoding GDNF have been cloned and sequenced. Methods and devices are disclosed for the delivery of GDNF using either an implantable cell which expresses human GDNF or a biocompatible semipermeable membrane containing genetically engineered cells which express and secrete the neurotrophic factor.