The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2001
Filed:
Aug. 19, 1998
Applicant:
Inventors:
Harald Dugstad, Oslo, NO;
Jo Klaveness, Oslo, NO;
Pål Rongved, Oslo, NO;
Roald Skurtveit, Oslo, NO;
Jorunn Brænden, Oslo, NO;
Assignee:
Nycomed Imaging AS, Oslo, NO;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/00 ; B32B 1/502 ;
U.S. Cl.
CPC ...
A61B 8/00 ; B32B 1/502 ;
Abstract
Microbubble dispersions stabilised by phospholipids predominantly comprising molecules which individually have an overall net charge exhibit advantageous stability, rendering them useful as efficacious contrast agents. An improved process for preparing microbubble-containing contrast agents is also disclosed, this comprising lyophilising an aqueous dispersion of gas microbubbles stabilised by one or more membrane-forming lipids to yield a dried product which may be reconstituted in an injectable carrier liquid to generate a microbubble-containing contrast agent.