The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2001
Filed:
Oct. 12, 1999
Analytical methods and apparatus employing an optical sensor device with refractive index modulation
Nikolai Mikhailovich Lyndin, Moscow, RU;
Vladimir Alexandrovich Sychugov, Moscow, RU;
Alexander Valentinovich Tishchenko, Moscow, RU;
Boris Alexandrovich Usievich, Moscow, RU;
Thermo Fast UK Limited, , GB;
Abstract
A method for monitoring the interaction of molecular species utilizes a sensor device comprising a substrate (,) with a waveguide (,) formed on the surface thereof. A grating (,) is formed in one of the surfaces of the waveguide (,). A beam of light (,) is incident on the grating (,) and the angle of incidence at which maximum reflection occurs is monitored. A first molecular species is immobilized on the waveguide (,). Changes in the angular position of the reflection maximum provide an indication of interaction of the first molecular species with a second molecular species contained in a sample brought into contact with the sensor device.