The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2001
Filed:
Jun. 05, 1995
Applicant:
Inventors:
Mepur H. Ravindranath, Los Angeles, CA (US);
Donald L. Morton, Malibu, CA (US);
Assignee:
John Wayne Cancer Institute, Santa Monica, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 4/500 ; A61K 3/940 ; A61K 3/9395 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 4/500 ; A61K 3/940 ; A61K 3/9395 ;
Abstract
Disclosed are compositions and methods for enhancing the antibody and T cell response to cellular antigens by incorporating an immunopotentiating agent into the cellular membrane or into an intracellular compartment. Such adjuvant-incorporated cell compositions are useful in methods to increase immune responses against antigens, including immunologically cryptic tumor cell antigens, and may be employed to generate useful diagnostic antibodies, to elicit anti-tumor effects in immunized animals, and to significantly prolong survival in animals with cancer.