The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2001

Filed:

Jun. 16, 1999
Applicant:
Inventors:

Bruce A. Littlefield, Andover, MA (US);

Monica H. Palme, San Jose, CA (US);

Boris M. Seletsky, Andover, MA (US);

Murray J. Towle, Auburn, NH (US);

Melvin J. Yu, Andover, MA (US);

Wanjun Zheng, Londonberry, NH (US);

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1335 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1335 ; C07D / ;
Abstract

The invention provides halichondrin analogs having pharmaceutical activity, such as anticancer or antimitotic (mitosis-blocking) activity, and methods of identifying agents that induce a sustained mitotic block in a cell after transient exposure of the cell to the agents.


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