The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2001

Filed:

May. 17, 1999
Applicant:
Inventors:

Leroy B. Townsend, Ann Arbor, MI (US);

John C. Drach, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/170 ; C07H 1/701 ; A01N 4/304 ;
U.S. Cl.
CPC ...
A61K 3/170 ; C07H 1/701 ; A01N 4/304 ;
Abstract

This invention pertains to nucleoside analogs that have antiviral activity and improved metabolic stability, compositions comprising them, and methods of antiviral treatment employing them. More particularly, this invention pertains to imidazo[1,2-a]pyridine C-nucleosides, as exemplified by compounds such as imidazo[l,2-a]pyridine C5-nucleosides and imidazo[1,2-a]pyridine C3-nucleosides, and may be represented by formula (I), wherein exactly one of Q,and Q,is a sugar-like moiety; exactly one of Q,and Q,is —H; and Q,, Q,, Q,and Q,are independently imidazo[1,2-a]pyridine substituents, such as —H, —F, —Cl, —Br and —I.


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