The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2001
Filed:
May. 12, 2000
Applicant:
Inventors:
Tomio Takeuchi, Tokyo, JP;
Masa Hamada, Tokyo, JP;
Yasuhiko Muraoka, Tokyo, JP;
Tetsuo Akiyama, Tokyo, JP;
Masatoshi Abe, Tokyo, JP;
Hiroshi Naganawa, Tokyo, JP;
Yoshikazu Takahashi, Tokyo, JP;
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 ; C12N 9/99 ; A61K 3/574 ; C07G 1/700 ; C12P 1/06 ;
U.S. Cl.
CPC ...
C12N 1/20 ; C12N 9/99 ; A61K 3/574 ; C07G 1/700 ; C12P 1/06 ;
Abstract
This invention provides a physiologically active substance having a strong dipeptidyl peptidase IV inhibitory activity. The physiologically active substance sulphostin is obtained by culturing a microorganism belonging to the genus Streptomyces and having an ability to produce the physiologically active substance sulphostin, producing and accumulating this substance in the cultures, and harvesting it from the cultures.