The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2001
Filed:
Jul. 08, 1999
Applicant:
Inventors:
Mario Fantucci, Milan, IT;
Francesco Santangelo, Milan, IT;
Assignee:
Zambon Group S.p.A., Vicenza, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 3/06 ; C07D / ;
U.S. Cl.
CPC ...
C07F 3/06 ; C07D / ;
Abstract
A process for the preparation of heteroaryl-zinc halides of the formula (II): Het—Zn—X, wherein Het is an optionally substituted 5 or 6 membered aromatic heterocyclic group with one or two heteroatoms selected among nitrogen, oxygen or sulphur; X is a chlorine, bromine or iodine atom; comprising metallation reaction of heteroarylhalide with metallic zinc optionally activated by washing with acids, is described. Compounds of the formula (II) are intermediates useful in the synthesis for the preparation of compounds endowed with pharmacological activity.