The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2001
Filed:
Aug. 31, 1998
Stanley D. Glick, Delmar, NY (US);
Martin E. Kuehne, Burlington, VT (US);
Other;
Abstract
The present invention is directed to compounds having formula (1), wherein n is from 0 to 8; R,is CH,OH, CH(OH)R,, CH,OR,, CO,R,, C(O)NH,, C(I)NHR,, C(O)NR,R,, C(O)NHNH,, C(O)NHNHR,, C(O)NHNR,R,, C(O)NR,NH,, C(O)NR,NHR,, C(O)NR,NR,R,, C(O)NHNH(C(O)R,), C(O)NHNR,(C(O)R,) C(O)NR,NH(C(O)R,), C(O)NR,NR,(C(O)R,), CN, or C(O)R,; R,is H, unsubstituted or substituted alkyl, YH, YR,, YC(O)R,, C(O)YR,, C(O)NH,, C(O)NHR,, C(O)NR,R,, NH,, NHR,, NR,R,, NHC(O)R,, or NR,C(O)R,; R,and R,are the same or different and are selected from the group consisting of H, halogens, unsubstituted or substituted alkyl, OH, OR,, NH,, NHR,, NR,R,, NHC(O)R,, or NR,C(O)R,; R,, R,, R,, R,, R,, R,, and R,are the same or different and are selected from the group consisting of unsubstituted alkyl and substituted alkyl and substituted alkyl; R,is selected from the group consisting of J, unsubstituted alkyl, and substituted alkyl; and Y is O or S; provided that when n is O, R,is selected from the group consisting of H, substituted alkyl, and unsubstituted alkyl; and pharmaceutically acceptable salts thereof. The compounds are useful in the treatment of subjects addicted to opiates and stimulants and have reduced side effects relative to other ibogamine congeners.