The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2001
Filed:
Mar. 31, 1999
Applicant:
Inventors:
Roderic M. K. Dale, Wilsonville, OR (US);
Steven L. Gatton, Lake Oswego, OR (US);
Amy Arrow, Bethel, ME (US);
Assignee:
Oligos Etc. Inc., Wilsonville, OR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 5/100 ; A01N 4/304 ; C12Q 1/68 ; C07H 2/102 ;
U.S. Cl.
CPC ...
A61K 5/100 ; A01N 4/304 ; C12Q 1/68 ; C07H 2/102 ;
Abstract
The present invention provides a method of treating bacterial respiratory infections by pulmonary administration of protonated/acidified nucleic acids. These modified nucleic acids are effective as bactericidal and/or bacteriostatic agents without regard to the class of bacteria, so are especially useful when diagnosis is difficult or when multiple infectious organisms are present. The antibiotic activity of nucleic acids of the invention is not dependent on either the specific sequence of the nucleic acid or the length of the nucleic acid molecule.