The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2001

Filed:

Sep. 12, 1997
Applicant:
Inventors:

Robert W. Finberg, Canton, MA (US);

Jeffrey M. Bergelson, Narberth, PA (US);

Marshall S. Horwitz, Larchmont, NY (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ;
U.S. Cl.
CPC ...
C12N 1/500 ;
Abstract

The invention provides isolated nucleic acid molecules which encode a coxsackievirus and adenovirus receptor protein, CAR. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CAR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a CAR gene has been introduced or disrupted. The invention still further provides isolated CAR proteins, fusion proteins, antigenic peptides and anti-CAR antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.


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