The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2001

Filed:

Oct. 08, 1999
Applicant:
Inventors:

Robert A. Zambias, San Diego, CA (US);

Daniel B. Kassel, Del Mar, CA (US);

Assignee:

CombiChem, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 1/508 ;
U.S. Cl.
CPC ...
B01D 1/508 ;
Abstract

Single pass methods and systems for measuring the total masses of individual compounds present in fluid samples in real time, and particularly for fluid samples prepared in microtiter plate format are provided. Individual compounds are isolated by fluid separation column (,). Portions of the individual compounds isolated by column (,) are analyzed by mass spectrometer (,), which determines their concentration on the basis of their molecular weights, and an evaporative light scattering detector (,), (which determines the total masses of each of the isolated compounds passing therethrough). Total collected masses of the individual compounds are calculated by determining the amount and portion of the isolated compounds diverted into evaporative light scattering detector (,) during a period of fraction collection.


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