The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2001
Filed:
Aug. 21, 1998
Robert R. Holloway, Montara, CA (US);
Agilent Technologies, Inc., Palo Alto, CA (US);
Abstract
The present invention relates to capillary columns including a monolith and a method for preparing a capillary column including a monolith. The monolith can be prepared by a sol gel method, and in the transformation from hydrosol to hydrogel, the monolith undergoes essentially no syneresis or volume shrinkage. Thus, deleterious effects of syneresis are avoided, such as the formation of channels having large dimensions that provide a pathway of least resistance for a mobile phase to effectively bypass portions of a stationary phase. The method for preparing a column having a monolith that undergoes essentially no syneresis involves a hydrogel solution that has a relatively low concentration of SiO,, i.e. less than about 5 g/100 mL.