The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2001

Filed:

Feb. 23, 1999
Applicant:
Inventors:

Oskar Axelsson, Malmo, SE;

Dan Peters, Arlov, SE;

Jorgen Scheel-Kruger, Glostrup, DK;

Elsebet Ostergaard Nielsen, Copenhagen, DK;

Assignee:

Neurosearch A/S, Glostrup, DK;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/155 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/155 ; C07D / ;
Abstract

The present invention relates to compounds of formula (I), any of it enantiomers, or any mixture thereof, or a pharmaceutically acceptable acid addition salt thereof, wherein R,, R,, R,, R,, R,, R,, R,, R,and R,each independently are hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, nitro, cyano, amino, acyl, alkylamino, dialkylamino, aminocarbonyl, or acylamino; R5 is hydrogen, alkyl, alkoxyalkyl, or phenylalkyl; X is —CH,—Z—, Z—CH,—, NH—CO—, —CO—NH—, or —CH═CH—; wherein Z is O, S, CH,, or NH; Y is O, —CH,—W—, —W—CH,—; wherein W is O, or S; and n is 0, 1 or 2. The compounds are useful in the treatment of psychotic disorders.


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