The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2001
Filed:
Apr. 16, 1999
Applicant:
Inventors:
Richard William Arthur Luke, Macclesfield, GB;
Ronald Cotton, Macclesfield, GB;
Assignee:
Zeneca Limited, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/155 ; A61K 3/808 ; C07D / ; C07K 7/02 ;
U.S. Cl.
CPC ...
A61K 3/155 ; A61K 3/808 ; C07D / ; C07K 7/02 ;
Abstract
The invention concerns pharmaceutically useful peptide derivatives of the formula (I), P—R,—R,—R,—R,, in which P, R,, R,, R,, and R,have the various meanings defined herein, and their pharmaceutically acceptable salts, and pharmaceutical compositions containing them. The novel peptide derivatives are of value in treating MHC class II dependent T-cell mediated autoimmune or inflammatory diseases, such as rheumatoid arthritis. The invention further concerns processes for the manufacture of the novel peptide derivatives and the use of the compounds in medical treatment.