The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2001
Filed:
Sep. 02, 1998
Jacek Rozga, Westlake Village, CA (US);
Achilles A. Demetriou, Bel Air, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
A bioreactor (,) comprises an elastic housing (,) and a plurality of hollow, porous fibers (,) disposed within the housing. The lumens of the fibers define an intrafiber compartment, and the outer surfaces of the fibers and the housing define an extrafiber compartment. A variable flow device (,) varies the flow of the perfusate through the intrafiber compartment. The variable flow device can include a flow restrictor (,) that variably restricts the discharge of a perfusate (,) from the intrafiber compartment or a pump for increasing the flow of the perfusate into the intrafiber compartment. The elastic housing can include a wall (,) with perforations (,) extending therethrough and an elastic membrane (,) tightly surrounding the wall or a wall with at least one expansion port extending therethrough and at least one extrafiber space expander,coupled to a one of the at least one expansion port.