The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2001
Filed:
Jun. 06, 1996
Applicant:
Inventors:
Edward Jess Victoria, San Diego, CA (US);
David Matthew Marquis, Encinitas, CA (US);
David S. Jones, San Diego, CA (US);
Lin Yu, San Diego, CA (US);
Assignee:
La Jolla Pharmaceutical Company, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9385 ; A61K 3/804 ;
U.S. Cl.
CPC ...
A61K 3/9385 ; A61K 3/804 ;
Abstract
aPL analogs that (a) bind specifically to B cells to which an aPL epitope binds and are disclosed. Optimized analogs lack T cell epitope(s) are useful as conjugates for treating aPL antibody-mediated diseases. Methods of preparing and identifying said analogs, methods of treatment using said analogs, methods and compositions for preparing conjugates of said analogs and diagnostic immunoassays for aPL antibodies are disclosed.