The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2001
Filed:
Dec. 29, 1998
Applicant:
Inventors:
Kae Jong Chung, Seoul, KR;
Joo Kyung Lee, Seoul, KR;
Joo Woong Park, Seoul, KR;
Dong Jin Seo, Kyungki-do, KR;
Sang Choon Lee, Seoul, KR;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/706 ;
U.S. Cl.
CPC ...
C12P 1/706 ;
Abstract
The present invention is related to a new method for producing ML-236B, a precursor of pravastatin sodium, in particular to a method for producing ML-236B lactone form(I), free acid form(II), sodium salt(III) shown in the formulae (I), (II), (III) by using a new microorganism isolated from soil. ML-236B is obtained from the culture broth of this microorganism and it is used as a substrate of pravastatin sodium which is a potent cholesterol-lowering agent used in treatment for hypercholesterolemia.