The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2001

Filed:

Jun. 07, 1995
Applicant:
Inventors:

W. Peter Hansen, Cambridge, MA (US);

Michael Cennerazzo, Weehauken, NJ (US);

Carl Theodore Edens, Columbia, MD (US);

Manish Kochar, Columbia, MD (US);

Assignee:

Sienna Biotech, Inc., Columbia, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/3543 ; G01N 3/3546 ; G01N 3/3552 ; G01N 3/3553 ;
U.S. Cl.
CPC ...
G01N 3/3543 ; G01N 3/3546 ; G01N 3/3552 ; G01N 3/3553 ;
Abstract

Disclosed are an optical flow particle apparatus and method for conducting a particle light scatter-based immunoassay for simultaneously measuring the presence or amount of one or more analytes in a fluid sample which involves the use of a reagent set for each analyte including first binding molecule-coated monodisperse microspheres and second binding molecule-coated colloidal particles in which at least one of the first or second binding molecules specifically binds a respective one of the analytes. In the case where more than one analytes are detected, each monodisperse microperse microsphere of a particular reagent set has a light scatter signal resolvable from that of microspheres of any other reagent set. Changes determined in the distributions of the measured light scatter signals for individual microspheres of each of the particular reagent sets are indicative of the presence or amount of the respective analyte(s) in the sample.


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