The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2001
Filed:
Sep. 08, 1999
Applicant:
Inventors:
Rongmin Huang, West Chester, OH (US);
Philip A. Christenson, Loveland, OH (US);
Ivica M. Labuda, Mahwah, NJ (US);
Assignee:
Givaudan S.A., Vernier, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/00 ; C07C 4/500 ; C07C 3/522 ;
U.S. Cl.
CPC ...
C12P 7/00 ; C07C 4/500 ; C07C 3/522 ;
Abstract
A method of producing nootkatone by laccase catalyzed oxidation of valencene. Valencene and a composition having laccase activity are reacted in the presence of an oxygen source, at a valencene concentration greater than 0.1%, to form valencene hydroperoxide. Optionally, a mediator and/or a solvent at a concentration that maintains laccase activity may also be included. The valencene hydroperoxide is degraded to form nootkatone, and nootkatone is then recovered. The method produces nootkatone in commercially viable yields.