The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2001
Filed:
Feb. 23, 1999
Applicant:
Inventors:
Amitabh Gaur, San Diego, CA (US);
Nicholas Ling, San Diego, CA (US);
Paul J. Conlon, Solana Beach, CA (US);
Assignee:
Neurocrine Biosciences, San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/462 ; C07K 1/400 ; A61K 3/828 ;
U.S. Cl.
CPC ...
C07K 1/462 ; C07K 1/400 ; A61K 3/828 ;
Abstract
The present invention is directed toward peptide analogues of insulin B chain that are generally derived from peptides comprising residues 9 to 23 of the native B chain sequence. The analogues are altered from the native sequence at position 12, 13, 15 and/or 16, and may be additionally be altered at position 19 and/or other positions. Pharmaceutical compositions containing these peptide analogues arc provided. The peptide analogues are useful for treating and inhibiting the development of diabetes.