The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2001

Filed:

Oct. 14, 1999
Applicant:
Inventors:

Ronald J. Biediger, Houston, TX (US);

Vanessa O. Grabbe, Sugar Land, TX (US);

George W. Holland, North Caldwell, NJ (US);

Jamal M. Kassir, Houston, TX (US);

Timothy P. Kogan, late of Escondido, CA (US);

Shuqun Lin, Huntingdon Valley, PA (US);

Robert V. Market, Pearland, TX (US);

Bore G. Raju, Fremont, CA (US);

Ian L. Scott, Albany, NY (US);

Chengde Wu, Houston, TX (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/138 ; A61K 3/1425 ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/138 ; A61K 3/1425 ; C07D / ; C07D / ; C07D / ;
Abstract

A method for the inhibition of the binding of &agr;,&bgr;,integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;,&bgr;,is involved.


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